广州医科大学学报

目的:探讨核磁共振(MRI)、钼靶X射线摄影和彩色多普勒超声(CDUS)单独或联合使用对未触及肿块乳腺癌早期诊断的实用价值。方法:150例未触及肿块的可疑乳腺疾病患者均行MRI、钼靶X射线摄影和CDUS检查,对其单独或并联检查的结果进行分析,并与病理结果进行对照。结果:MRI、钼靶X射线摄影、CUDS单独或联合使用与病理结果呈正关联,以上3种方法单独应用的诊断效能两两比较差异无统计学意义(P>0.05),MRI并联钼靶摄影、MRI并联CDUS、钼靶摄影并联CDUS以及3种方法并联应用的诊断效能比较,差异均无统计学意义(P>0.05),但上述4种并联应用方法的诊断效能均高于单独应用的诊断效能。相对而言,钼靶X射线摄影与CUDS并联检查可明显提高未触及肿块的乳腺癌的检出阳性率和灵敏度,诊断效能最好。结论:MRI、CDUS、钼靶X射线摄影单独或联合使用均可应用于未触及肿块的乳腺癌早期诊断,结合我国的实际情况,钼靶X射线摄影与CUDS联合应用可作为未触及肿块的乳腺癌的首选筛查方法。但MRI也有一定的临床应用价值。

Objective:To evaluate the value of the singly or parallel using with magnetic resonance imaging(MRI),mammography,color Doppler ultrasound(CDUS) in early detecting non-palpable breast cancer.Methods:150 female patients with suspicious masses underwent MRI,mammography and CDUS.The results of the histopathology after surgery were using as diagnostic golden standard.The findings of singly or parallel using of MRI,mammography and CDUS in non-palpable breast carcinoma were compared.Results:The results of singly or parallel using of MRI,mammography,CUDS for the diagnosis of the non-palpable breast cancer is related to the histopathology.In the diagnostic ability,the singly using of the three methods and the parallel using of two or three methods there were no significant difference showed.But,the diagnostic ability of the parallel using is highly than the singly using.Relatively,the combine diagnosis using of mammography and CDUS can improve the sensitivity significantly and the positive detectable rate.So,it was the most efficient.Conclusions:It's suitable that the singly using of MRI,mammography,CUDS and the parallel diagnosis using two or three of the methods together for the diagnosis of the non-palpable early breast cancer.The combine diagnosis using mammography and CDUS represented the best method for screening non-palpable early breast cancer in China.But,MRI has practical value of clinical application.