广州医科大学学报

14例“咳嗽型哮喘”的患者给予服用中药咳喘定煮散为实验组,另14例则服用支气管解痉药作对照治疗期共两个月。于治疗前及治疗后2-12个月进行吸入组织胺支气管激发试验。结果表明实验组有13/14例症状消失,一例转化为哮喘,支激试验转阴者达10/14例。而对照组则分别为9/14、4/14和3/14例。统计学结果表明实验组治疗有效率(92.9%)和支气管激发试验转阴率(71.4%)都显著高于对照组(50%和21.4%),P值为<0.05和<0.01,从而提示中药咳喘定煮散治疗本症比支气管解痉剂有更好疗效,其机制在于能改善气道高反应性。

An experimental group of 14 cases were treated by the Chinese traditional medicine KE QUANG DIN" and 14 controls were recieved the brochial spasmolysent for two months. The provocation tests of bronchi with histamin were performed before the treatment and after 2-12 months of treatment. The results showed that cough of 13/14 patients had disappeared, the airway hyperresponsiveness of 10/14 cases become negative and only one changed into typical asthma. However, there were 9/14, 4/14, and 3/14 cases separately in control group. The statistical results proved the treated response rate (92. 9%) and the response rate of airway hyperresponsiveness (71.4%) were higher than that in control group (50%, 21. 4%), P<0.05 and<0.01. This paper suggested the Chinese traditional drug "KE QUANG DIN" treating this disease was more effective than spasmolysent because it improved there airway hyperresponsiveness.