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目的:研究发热儿童血降钙素原(PCT)水平及其与C反应蛋白(CRP)及WBC的关系。方法:收集2012年1月至2013年5月中山大学孙逸仙纪念医院收治的32例急性发热儿童作为研究对象。根据血WBC水平分为A组16例(WBC升高);B组为16例(WBC正常或降低)。收集年龄、性别相匹配的32例健康儿童为正常对照组。检测血PCT、CRP及WBC水平。结果:A组患者血PCT水平高于B组和正常对照组(P<0.05);A组患者血CRP水平高于正常对照组(P<0.05);B组血PCT、CRP水平明显高于正常对照组(P<0.05)。A组患者血PCT水平与CRP、WBC水平呈正相关关系(r=0.68,r=0.76,P<0.05);而B组血PCT水平与CRP、WBC水平无相关关系(P>0.05)。结论:发热儿童血PCT升高伴随血WBC升高,二者具有正相关关系。
Abstract：Objective:To investigate the relationship of procalcitonin(PCT) levels with C-reactive protein(CRP) and white blood cell count(WBC) in febrile children.Methods:Between January 2012 and May 2013,we recruited 32 febrile children from the department of medical laboratory testing,Sun Yat-sen Memorial Hospital.Children were allocated to group A(n = 16,characterized by increased WBC) and group B(re = 16,characterized by normal or decreased WBC).We also enrolled 32 healthy children as the control group.This entailed measurement of the levels of PCT,CRP and WBC.Results;The levels of PCT(4.06 ± 0.79)(Ag/L)and CRP(46.3 ± 19.3) mg/L were highest in group A,followed by group B and normal control group(all P <0.05).In group A,there was a positive correlation between PCT and CRP or WBC(r = 0.68 and 0.76,both P< 0.05).However,these relations were absent in group B(all P > 0.05).Conclusion:The increased levels of PCT which are accompanied by augmented WBC in febrile children are positively correlated with each other.
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基本信息:
中图分类号:R441.3
引用信息:
[1]曾华,方伟祯,陈经纬.发热儿童血PCT水平及其与CRP和WBC的关系[J].广州医学院学报,2013,41(05):81-83.