广州医科大学学报

参考文献

[1] Mevel R, Draper JE, Lie-A-Ling M, et al. RUNX transcription factors:orchestrators of development[J].Development,2019,146(17):dev148296.

[2] Samarakkody AS, Shin NY, Cantor AB. Role of RUNX Family Transcription Factors in DNA Damage Response[J].Mol Cells,2020,43(2):99-106.

[3] Ito Y,Bae SC,Chuang LS.The RUNX family:developmental regulators in cancer[J].Nat Rev Cancer,2015,15(2):81-95.

[4] Lee JW,Kim DM, Jang JW, et al. RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point[J]. Nat Commun,2019,10(1):1897.

[5] Martinez M,Hinojosa M,Trombly D,et al. Transcriptional Auto-Regulation of RUNX1 P1 Promoter[J].PLoS One,2016,11(2):e0149119.

[6] Voon DC, Hor YT, Ito Y. The RUNX complex:reaching beyond haematopoiesis into immunity[J]. Immunology,2015,146(4):523-536.

[7] Morita K,Suzuki K,Maeda S,et al.Genetic regulation of the RUNX transcription factor family has antitumor effects[J].J Clin Invest,2017,127(7):2815-2828.

[8] Sweeney K, Cameron ER, Blyth K. Complex Interplay between the RUNX Transcription Factors and Wnt/β-Catenin Pathway in Cancer:A Tango in the Night[J].Mol Cells,2020,43(2):188-197.

[9] Lluri G, Huang V, Touma M, et al. Hematopoietic progenitors are required for proper development of coronary vasculature[J]. J Mol Cell Cardiol,2015,86:199-207.

[10] Górnikiewicz B,Ronowicz A,Krzemiński M,et al.Changes in gene methylation patterns in neonatal murine hearts:Implications for the regenerative potential[J]. BMC Genomics,2016,17:231.

[11] Riddell A, McBride M, Braun T, et al. RUNX1:an emerging therapeutic target for cardiovascular disease[J].Cardiovasc Res,2020,116(8):1410-1423.

[12] McCarroll CS, He W, Foote K, et al. Runx1 Deficiency Protects Against Adverse Cardiac Remodeling After Myocardial Infarction[J].Circulation,2018,137(1):57-70.

[13] Koth J,Wang X,Killen AC,et al. Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration[J].Development,2020,147(8):dev186569.

[14] Golan-Lagziel T,Lewis YE,Shkedi O,et al.Analysis of rat cardiac myocytes and fibroblasts identifies combinatorial enhancer organization and transcription factor families[J].J Mol Cell Cardiol,2018,116:91-105.

[15] Tang X, Sun L, Jin X, et al. Runt-Related Transcription Factor 1 Regulates LPS-Induced Acute Lung Injury via NF-κB Signaling[J].Am J Respir Cell Mol Biol,2017,57(2):174-183.

[16] Lam JD,Oh DJ,Wong LL,et al.Identification of RUNX1as a Mediator of Aberrant Retinal Angiogenesis[J].Diabetes,2017,66(7):1950-1956.

[17] Wu CM,Zheng L,Wang Q,et al.The emerging role of cell senescence in atherosclerosis[J]. Clin Chem Lab Med,2020,59(1):27-38.

[18] Chen Y,Zhao X,Wu H. Transcriptional Programming in Arteriosclerotic Disease:A Multifaceted Function of the Runx2(Runt-Related Transcription Factor 2)[J].Arterioscler Thromb Vasc Biol,2021,41(1):20-34.

[19] Sun Y, Byon CH, Yuan K, et al. Smooth muscle cellspecific runx2 deficiency inhibits vascular calcification[J].Circ Res,2012,111(5):543-552.

[20] Lin ME, Chen T, Leaf EM, et al. Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice[J]. Am J Pathol,2015,185(7):1958-1969.

[21] Deng L,Huang L,Sun Y,et al. Inhibition of FOXO1/3promotes vascular calcification[J]. Arterioscler Thromb Vasc Biol,2015,35(1):175-183.

[22] Yang Y,Sun Y,Chen J,et al.AKT-independent activation of p38 MAP kinase promotes vascular calcification[J].Redox Biol,2018,16:97-103.

[23] Zhu L, Zhang N, Yan R, et al. Hyperhomocysteinemia induces vascular calcification by activating the transcription factor RUNX2 via Krüppel-like factor 4 upregulation in mice[J]. J Biol Chem, 2019, 294(51):19465-19474.

[24]éva Sikura K,Combi Z,Potor L,et al. Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization[J].J Adv Res,2021,27:165-176.

[25] Tavares A,Brown JA,Ulrich EC,et al.Runx2-I is an Early Regulator of Epithelial-Mesenchymal Cell Transition in the Chick Embryo[J].Dev Dyn,2018,247(3):542-554.

[26] Piera-Velazquez S, Jimenez SA. Endothelial to Mesenchymal Transition:Role in Physiology and in the Pathogenesis of Human Diseases[J]. Physiol Rev,2019,99(2):1281-1324.

[27] Bischoff J.Endothelial-to-Mesenchymal Transition[J].Circ Res,2019,124(8):1163-1165.

[28] Wang Y, Yang X, Jiang A, et al. Methylation-dependent transcriptional repression of RUNX3 by KCNQ1OT1regulates mouse cardiac microvascular endothelial cell viability and inflammatory response following myocardial infarction[J].FASEB J,2019,33(12):13145-13160.

[29] Laugier L, Frade AF, Ferreira FM, et al. Whole-genome cardiac dna methylation fingerprint and gene expression analysis provide new insights in the pathogenesis of chronic chagas disease cardiomyopathy[J]. Clin Infect Dis,2017,65(7):1103-1111.