广州医科大学学报

目的:评价用完美强脉冲光(OPT)治疗伴有黄褐斑的面部雀斑患者临床疗效及安全性。方法:82例伴有黄褐斑的雀斑患者,全部采用OPT治疗5次,间隔3⁴周治疗1次,完成5次治疗随访1月后留取治疗前后照片观察疗效,所有患者都要求严格防晒,勿过度劳累。结果:经过5次OPT治疗后,雀斑治愈70例(85.36%);显效9例(10.98%);雀王i￡总有效率96.34%(79/82)。黄褐斑治愈0例(0%);显效51例(62.20%);黄褐斑总有效率51例62.20%(51/82)。不良反应:有7例(8.54%)出现色素沉着,经过3⁶个月后色素明显减淡;有2例(2.44%)出现色素减退,未出现瘢痕。结论:OPT治疗伴有黄褐斑的雀斑患者安全、高效,大部分雀斑患者治愈,黄褐斑得到明显改善,但黄褐斑治愈率不高仍是一个现实问题,有待我们进一步研究和探讨。

Objective:To evaluate the effectiveness and safty of intense pulsed light with Optimal Pulse Technology(OPT) in the treatment of patients accompanied with facial freckles and melasma.Methods:A Study was performed in 82 patients accompanied with facial freckles and melasma who visited the Plastic Laser Center of the Second Affiliated Hospital of GuangZhou Medical Uni versity.82 patients have received with 5 times consecutive OPT treatments interval 3~4weeks.Follow up a month and take photos of patients befoe and after treatments.It used to judge the clinical effectiveness.All of patients were strict with sun-proof.Results:The cure rate of the freckles was 85.36 per cent.The melasma was 0 per cent.The total effective rate of the freckles was 96.34 per cent.The melasma was 62.20 per cent.The side-effects were also observed.Hyperpigmentation was8.54 per cent.Hypopigmentation is 2.44 per cent.Hypertrophic scar was not founded.Conclusions:Intense pulsed light with Optimal Pulse Technology(OPT) were effective and safe in treatment of patients accompanied with facial freckles and melasma.